Not All Probiotics Are Equal
1. Make it to the Gut
An article published by the American Chemical Society puts it this way, “Probiotics are living organisms [that can] have beneficial effects when they colonize the body, assuming they can stay alive long enough to do so. Probiotic treatments are packed with bacteria, but once swallowed, their numbers are dramatically diminished by the stomach’s acidity…” While this article discusses efforts to create a gel capsule for safe probiotic passage, another way probiotics can make it to the gut and be effective is by using proper bacterial strains and appropriate dosing.
2. The Strains
Different bacterial strains have different functions and interactions within the gut. A random assortment of bacterial strains thrown together to make a probiotic is like trying to make a house out of random materials. The bacterial strains included in a probiotic should work well together to create and support a healthy and balanced gut.
For example, a 2019 study reviewed the effects of Lactobacillus plantarum and Lactobacillus paracasei in a randomized, double-blind, placebo-controlled clinical trial. The study specifically focused on how these two strains of bacteria affected the severity, duration, and frequency of the common cold. The study found that, “the severity and duration of common cold episodes are reduced upon ingestion of the specific probiotic product. Symptoms of cold were alleviated throughout the entire cold episodes, which in turn affected the duration of the episodes.” Nevertheless, this study focused on only two specific bacterial strains and one specific health issue. Not all bacterial strains work the same or elicit the same effects, that’s why it’s important to choose a probiotic with the right strains to create and support a healthy and balanced gut. Supportingly, one article states that, “the efficacy of probiotics is strain specific, decades of research have shown that only specific strains of bacteria or fungus have health benefits.”
3. The Dosing
Both quality and quantity matter when it comes to probiotics. Probiotics are quantified in colony forming units (CFUs) – individual cells growing together as a cluster. Probiotics must contain a high dose (think high CFUs) of appropriately paired strains of bacteria that work well together in order to be beneficial.
For instance, typical probiotic supplements contain 1-10 billion CFUs and can have positive effects on the gut. Notwithstanding, one article states that, “doses of between 200 billion and several trillion CFU of products consisting of mixed probiotic strains should be considered safe for adjunct therapies for patients with IBD, IBS and AAD.”  (IBD = Inflammatory Bowel Disease, IBS = Irritable Bowel Syndrome, AAD = Antibiotic Associated Diarrhea)
4. Method of Storage
5. Proof of Efficacy
Any probiotic you are considering should have proof that backs up its claims for human efficacy. Surprisingly, there are very few probiotic supplements that have actually been researched in clinical trials using human subjects. Additionally, independent non-clinical studies of consumer probiotics have illuminated the casm of what is vs. what is claimed.
“Several studies have found discrepancies from what was stated on the product label versus independent testing of the ingredients including lower levels of microbes, not finding the labeled strain or finding contamination of other strains in the product.”
LYVECAP Probiotic Facts
- Formulated by Professor Claudio De Simone, distinguished scientist and medical doctor—a pioneer in the field of intestinal microflora recognized internationally, his formulation (the De Simone Formulation) has been the subject of more than 200 publications and 70 published clinical trials
- The De Simone Formulation is the foundation of every LYVECAP product.
- Contains a high potency blend of properly paired bacterial strains that clinically make a difference (100+ billion CFUs, 8 hand-picked strains)
- LYVECAP’s patented probiotic delivery system has been tested and is proven to keep bacteria alive within the cap—maintaining and preserving the De Simone Formulation.
- Always stocked and shipped in a refrigerated environment (39 – 46 °F)